Subacute Combined Degeneration One Century Later. The Neurotrophic Action of Cobalamin (Vitamin B12) Revisited
نویسندگان
چکیده
منابع مشابه
Vitamin B12 in the pathogenesis of subacute combined degeneration of the spinal cord.
T h e etiopathogenesis of subacute combined degeneration of the spinal cord ( S C D S C ) is still a mat ter of controversy. In spite of the numerous investigations made in the last years, concerning particularly the metabolism of vi tamin B 1 2 , some fundamental aspects of the disease process are still unknown. I t is granted that the finding of deficient absorption of vitamin B 1 2 and/or th...
متن کاملSubacute combined degeneration : report of two cases
Subacute combined degeneration ( SCD) due to vitamin B12 deficiency is common in North of Europe but sometimes it is seen in Iran. It can develop before the symptoms of anemia is obvious, with myelin injury and then axon and even neuron destruction in spinal cord, brain, optic and peripheral nerves. In this study two cases are reported; in the first patient, this disease in manifested by vitami...
متن کاملSubacute combined degeneration of the spinal cord due to vitamin B12 deficiency.
1 of 3 DESCRIPTION A previously healthy 82-year-old lady presented with abnormal sensation in her fi ngers which she described as ‘feeling like bananas’. There was an additional history of deteriorating handwriting and a sense of imbalance when walking dating back 6 months. She obtained a score of 26 out of 30 on the mini mental state examination. She had gait ataxia, being unable to perform ta...
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Schimana R, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-222446 Description A 67-year-old man with a medical history of pancreatoduodenectomy (Whipple procedure) in September 2015 due to a pancreatic cancer was admitted to our department of neurology 1 year later with a progressively disturbed gait. He reported weakness and numbness of both legs. Clinical examination revealed a spastic sensom...
متن کاملRehabilitation of the patient with subacute combined degeneration of the spinal cord in the course of vitamin B12 deÞ ciency
Objective. We present a case of a man diagnosed with the spinal cord degeneration (SCD) in the course of vitamin B12 deÞ ciency, along with the rehabilitation used in his therapy. Case. The Þ rst symptoms occurred in December 2011. The reason for the patient’s functional dysfunction was recognised in January 2012, and the patient was subsequently admitted to the rehabilitation unit in June 2012...
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ژورنال
عنوان ژورنال: Journal of Neuropathology & Experimental Neurology
سال: 2001
ISSN: 0022-3069,1554-6578
DOI: 10.1093/jnen/60.2.109